Evaluating the Role of Nurse-Led Education in Enhancing Medication Compliance

Abstract

Medication non-adherence represents a critical global healthcare challenge, contributing to increased morbidity, mortality, and healthcare expenditure. Nurse-led educational interventions have emerged as a promising strategy to address this persistent problem, particularly in chronic disease management. This study aims to evaluate the effectiveness of nurse-led educational interventions in improving medication compliance among patients with chronic diseases, assess the impact on clinical outcomes, identify barriers to medication adherence, and determine the sustainability of improved adherence patterns following nurse-led interventions. A systematic review approach was employed, analyzing randomized controlled trials and quasi-experimental studies published between 2020-2024. The study focused on nurse-led educational interventions targeting medication adherence in chronic disease populations including hypertension, diabetes mellitus, cardiovascular diseases, and multimorbidity conditions. Data synthesis included meta-analysis of adherence rates, clinical outcomes, and patient satisfaction metrics.

Nurse-led educational interventions demonstrated significant improvements in medication adherence rates, with face-to-face interventions showing 71.4% effectiveness and mixed-method approaches achieving 44.4% success rates. Remote interventions demonstrated 16.7% effectiveness. Clinical outcomes including blood pressure control, glycemic management, and hospitalization rates showed statistically significant improvements in intervention groups compared to usual care. Nurse-led educational interventions constitute an effective, evidence-based strategy for enhancing medication compliance across diverse chronic disease populations.