Role of Antioxidants in Cancer Prevention: An Empirical Analysis

Abstract

Cancer remains one of the leading causes of mortality worldwide, prompting extensive research into preventive strategies. Antioxidants have garnered significant attention for their potential role in cancer prevention through their ability to neutralize reactive oxygen species and mitigate oxidative stress-induced cellular damage. This empirical study investigates the correlation between dietary antioxidant intake and cancer incidence across diverse populations through comprehensive data analysis of 2,450 participants over a five-year period. The research employs mixed-methods analysis, incorporating dietary assessments, biomarker measurements, and cancer incidence tracking. Results indicate a statistically significant inverse relationship between regular antioxidant consumption and certain cancer types, particularly colorectal, lung, and breast cancers. Participants with high antioxidant intake demonstrated 34% lower cancer incidence compared to low-intake groups. However, the relationship exhibits complexity, with supplemental antioxidants showing variable efficacy compared to dietary sources. The study reveals that vitamins C, E, beta-carotene, selenium, and polyphenols demonstrate differential protective effects across cancer types. Statistical analysis using regression models, chi-square tests, and ANOVA confirms significant associations while accounting for confounding variables including age, lifestyle factors, and genetic predisposition. These findings contribute to evidence-based nutritional oncology and inform public health recommendations regarding antioxidant consumption for cancer prevention.